Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.77 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.77 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.77 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL318020 | 1.00 | — | — | |
| Glycine SCHEMBL7918812 | 1.00 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL11291516 | 1.00 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL29244710 | 1.00 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL1285648 | 0.96 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL3343294 | 0.96 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL11443527 | 0.96 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL11421944 | 0.96 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL20854478 | 0.96 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2FFAR3LCK | |
| Glycine SCHEMBL5328855 | 0.96 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171715-A1 | DETERGENT AND CLEANING AGENT CONTAINING ANTIMICROBIAL PEPTIDE | HENKEL AG & CO. KGAA (DE) | 2025-05-29 | — | — | US | claimed |
| CN-119968190-A | Composition for caring keratin materials and dressing film containing the same | 莱雅公司 | 2025-05-09 | — | — | CN | claimed |
| EP-4414443-A1 | CLEANING COMPOSITION COMPRISING POLYESTERASE | Henkel AG & Co. KGaA (DE) | 2024-08-14 | — | — | EP | claimed |
| WO-2024103534-A1 | POLYURETHANE CURING AGENT, PREPARATION METHOD THEREFOR, AND USE THEREOF | 江苏奥斯佳材料科技股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| CN-117920735-A | Stabilization method for copper-containing dangerous waste residues | 中国恩菲工程技术有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117510727-A | Sustained-release salt-resistant humic acid super absorbent resin and preparation method thereof | 陕西科技大学 | 2024-02-06 | — | — | CN | claimed |
| CN-117500476-A | Composition for cleaning and/or removing makeup from keratin materials | 莱雅公司 | 2024-02-02 | — | — | CN | claimed |
| EP-4301504-A1 | PROCESS FOR MAKING A PARTICULATE COATED ORGANIC SALT, AND PARTICULATE COATED SALT | BASF SE (DE) | 2024-01-10 | — | — | EP | claimed |
| US-20230337673-A1 | HERBICIDAL COMPOSITION BASED ON TOPRAMEZONE OR SALT ACTIVE SUBSTANCE THEREOF | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) | 2023-10-26 | — | — | US | claimed |
| CN-116806139-A | Dual phase composition for cleansing and/or removing makeup from keratin materials | 莱雅公司 | 2023-09-26 | — | — | CN | claimed |
| CN-111304008-B | Liquid detergent composition with antibacterial function in low-hardness water environment | 纳爱斯浙江科技有限公司 | 2021-05-28 | — | — | CN | claimed |
| EP-3810769-A1 | AUTOMATIC DISHWASHING DETERGENT COMPOSITION | The Procter & Gamble Company (US) | 2021-04-28 | — | — | EP | claimed |
| CN-111620790-A | Production method and production device of glycine diacetic acid derivative chelating agent | 曹清清 | 2020-09-04 | — | — | CN | claimed |
| CN-111304008-A | Liquid detergent composition with antibacterial function in low-hardness water environment | 纳爱斯浙江科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| EP-3360986-B1 | STAINLESS STEEL SURFACE OXIDE COATING ACID-WASH ADDITIVE, MANUFACTURING METHOD, AND ACID WASHING METHOD | SHANXI ADD NEW ADDITIVE TECH CO LTD (CN) | 2020-03-25 | — | — | EP | claimed |
| US-20190119820-A1 | ACID-PICKLING ADDITIVE FOR SURFACE OXIDE SCALE OF STAINLESS STEEL MATERIAL, PREPARATION METHOD THEREOF, AND ACID-PICKLING METHOD | ADD NEW TECHNOLOGY DEVELOPMENT (SHANXI) CO., LTD. (CN) | 2019-04-25 | — | — | US | claimed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | claimed |
| US-9175931-B2 | Pressure impulse mitigation | FLEXIBLAST PTY LTD. (AU) | 2015-11-03 | — | — | US | claimed |
| US-8828134-B2 | Pressure impulse mitigation | FLEXIBLAST PTY LTD. (AU) | 2014-09-09 | — | — | US | claimed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171715-A1 | DETERGENT AND CLEANING AGENT CONTAINING ANTIMICROBIAL PEPTIDE | VIP, IDE, PEPD | GLRA1 4531/4885SLC6A9 4822/4885OR51E2 1832/4885 |
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | GLRA1 69/4885SLC6A9 1336/4885OR51E2 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.