Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653126 | 0.88 | HDAC1 (0.61) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL2651153 | 0.80 | HDAC1 (0.52) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL2652187 | 0.79 | HDAC1 (0.54) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL9070781 | 0.79 | HDAC1 (0.54) | HDAC1HDAC8TP53PLK1SMN1; SMN2 | |
| SCHEMBL2652410 | 0.79 | HDAC1 (0.52) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL2651574 | 0.78 | HDAC1 (0.50) | HDAC1HDAC8PLK1EHMT2EHMT1 | |
| SCHEMBL2665472 | 0.78 | HDAC1 (0.51) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL2650851 | 0.77 | HDAC1 (0.50) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL2651954 | 0.76 | EHMT2 (0.47) | HDAC1HDAC8TP53MAPTPLK1 | |
| SCHEMBL2652045 | 0.74 | ENPP2 (0.51) | TP53MAPTSMN1; SMN2EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053938-A1 | BENZIMIDAZOLS AND INDOLS AS GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTEN | NOVO NORDISK A/S (DK) | 2003-07-03 | — | — | WO | disclosed |