Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667507 | 1.00 | GCK (0.62) | GCKKCNH2SMN1; SMN2BRD4MAPT | |
| SCHEMBL2667508 | 1.00 | GCK (0.62) | GCKKCNH2SMN1; SMN2BRD4MAPT | |
| SCHEMBL2667721 | 0.89 | GCK (0.56) | GCKKCNH2SMN1; SMN2BRD4MAPT | |
| SCHEMBL2667615 | 0.89 | GCK (0.58) | GCKKCNH2SMN1; SMN2BRD4MAPT | |
| SCHEMBL2667602 | 0.88 | SMN1; SMN2 (0.59) | GCKSMN1; SMN2BRD4MAPTALDH1A1 | |
| SCHEMBL2667567 | 0.87 | GCK (0.63) | GCKKCNH2RAB9ANPC1 | |
| SCHEMBL9070913 | 0.87 | GCK (0.56) | GCKKCNH2SMN1; SMN2BRD4MAPT | |
| SCHEMBL9070865 | 0.87 | SMN1; SMN2 (0.50) | GCKKCNH2SMN1; SMN2BRD4MAPT | |
| SCHEMBL2667796 | 0.86 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL2667588 | 0.86 | GCK (0.66) | GCKKCNH2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |