Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GCK | P35557 | 3/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070999 | 0.88 | RAB9A (0.63) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL9070879 | 0.88 | GCK (0.62) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667507 | 0.88 | GCK (0.62) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667508 | 0.88 | GCK (0.62) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667721 | 0.87 | GCK (0.56) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL9070865 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL9070829 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667933 | 0.87 | LMNA (0.43) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667594 | 0.86 | GCK (0.49) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL9070875 | 0.86 | GCK (0.56) | SMN1; SMN2BRD4MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |