Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667388 | 0.90 | GCK (0.57) | GCKKCNH2PTGDR | |
| SCHEMBL944565 | 0.89 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2667664 | 0.89 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2667559 | 0.88 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL9070853 | 0.87 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL2667688 | 0.85 | GCK (0.63) | GCKKCNH2 | |
| SCHEMBL2667553 | 0.85 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL2667973 | 0.85 | GCK (0.77) | GCKKCNH2 | |
| SCHEMBL2667519 | 0.85 | PTGDR (0.56) | GCKKCNH2PTGDR | |
| SCHEMBL2667589 | 0.84 | GCK (0.67) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |