Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070831 | 0.93 | MAPK1 (0.53) | ALDH1A1MAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL2667699 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL2667782 | 0.92 | ALDH1A1 (0.53) | ALDH1A1MAPK1HTTSMN1; SMN2TRPV4 | |
| SCHEMBL9070994 | 0.92 | MAPK1 (0.51) | ALDH1A1MAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9070953 | 0.92 | SCD (0.46) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9070840 | 0.91 | ALDH1A1 (0.54) | ALDH1A1MAPK1HTTSMN1; SMN2TRPV4 | |
| SCHEMBL2667729 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MAPK1HTTSMN1; SMN2TRPV4 | |
| SCHEMBL9071053 | 0.86 | GCK (0.55) | ALDH1A1MAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL2667974 | 0.86 | GCK (0.53) | ALDH1A1MAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL2667758 | 0.85 | MAPK1 (0.63) | ALDH1A1MAPK1HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |