Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PLAT | P00750 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017899 | 0.87 | PARP10 (0.53) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL14017929 | 0.82 | PARP10 (0.47) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL9071440 | 0.81 | PARP10 (0.50) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL14017925 | 0.81 | PARP10 (0.53) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL22089990 | 0.80 | PARP10 (0.56) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL30986197 | 0.80 | PARP10 (0.56) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL9071474 | 0.79 | GCK (0.53) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL27443684 | 0.79 | PARP1 (0.62) | PARP10PLAUF2KMT2APARP1 | |
| SCHEMBL13703974 | 0.78 | PARP10 (0.58) | PARP10PLAUF2PRSS1PLG | |
| SCHEMBL12127897 | 0.78 | PARP10 (0.58) | PARP10PLAUF2PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003015774-A1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2003-02-27 | — | — | WO | disclosed |