Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 7/20 | 0.47 |
| ▸ | CDK2 | P24941 | 7/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.44 |
| ▸ | CCND3 | P30281 | 3/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.44 |
| ▸ | CDK1 | P06493 | 4/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.43 |
| ▸ | CCND1 | P24385 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669487 | 0.88 | HDAC1 (0.47) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2669345 | 0.86 | HDAC1 (0.47) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2668616 | 0.84 | HDAC1 (0.48) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2668480 | 0.82 | HDAC3 (0.49) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL9071934 | 0.80 | MAPK10 (0.54) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL9071951 | 0.79 | KMT2A (0.50) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2668621 | 0.79 | GLS (0.46) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2668622 | 0.78 | CCNE1 (0.43) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2668627 | 0.77 | MAOB (0.46) | CCNE1CDK2CCNE2HDAC3HDAC4 | |
| SCHEMBL2668566 | 0.76 | CCNE1 (0.44) | CCNE1CDK2CCNE2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |