Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CDK4 | P11802 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCND1 | P24385 | 3/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241648 | 0.92 | KMT2A (0.44) | GCKKMT2ACDK2CCNE2CCNE1 | |
| SCHEMBL1238582 | 0.88 | STK17B (0.39) | GCKKMT2ACDK2CCNE2CCNE1 | |
| SCHEMBL2656007 | 0.87 | KMT2A (0.42) | GCKKMT2ACDK2CCNE2CCNE1 | |
| SCHEMBL2656005 | 0.87 | KMT2A (0.42) | GCKKMT2ACDK2CCNE2CCNE1 | |
| SCHEMBL1238617 | 0.86 | GCK (0.43) | GCKCDK2CCNE2CCNE1CCNB2 | |
| SCHEMBL2668705 | 0.86 | GCK (0.43) | GCKCDK2CCNE2CCNE1CCNB2 | |
| SCHEMBL1240698 | 0.85 | ROCK2 (0.44) | GCKCDK2CCNE2CCNE1CCNB2 | |
| SCHEMBL2668609 | 0.85 | ROCK2 (0.44) | GCKCDK2CCNE2CCNE1CCNB2 | |
| SCHEMBL1241440 | 0.84 | CCNE1 (0.41) | KMT2ACDK2CCNE2CCNE1CCNB2 | |
| SCHEMBL1238496 | 0.84 | CCNE2 (0.39) | GCKCDK2CCNE2CCNE1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |