Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | ADCYAP1R1 | P41586 | 6/20 | 0.55 |
| ▸ | GCGR | P47871 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072177 | 0.93 | KMT2A (0.65) | AGTR1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2664364 | 0.86 | ADCYAP1R1 (0.60) | KMT2ANPC1RAB9AADCYAP1R1GCGR | |
| SCHEMBL2664365 | 0.85 | NPC1 (0.59) | KMT2APOLBNPC1RAB9AADCYAP1R1 | |
| SCHEMBL2664386 | 0.84 | GCGR (0.73) | AGTR1KMT2APOLBGCGR | |
| SCHEMBL2664426 | 0.83 | ADCYAP1R1 (0.56) | KMT2APOLBNPC1RAB9AADCYAP1R1 | |
| SCHEMBL2664458 | 0.82 | GCGR (0.58) | NPC1RAB9AADCYAP1R1GCGRSMN1; SMN2 | |
| SCHEMBL9072264 | 0.81 | ADCYAP1R1 (0.55) | NPC1RAB9AADCYAP1R1GCGRSMN1; SMN2 | |
| SCHEMBL9072403 | 0.81 | ADCYAP1R1 (0.64) | KMT2ANPC1RAB9AADCYAP1R1GCGR | |
| SCHEMBL2664199 | 0.80 | ADCYAP1R1 (0.62) | ADCYAP1R1GCGR | |
| SCHEMBL2664192 | 0.80 | ADCYAP1R1 (0.64) | KMT2APOLBNPC1RAB9AADCYAP1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |