Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970448 | 0.82 | — | — | |
| Acrylic Acid SCHEMBL907450 | 0.80 | GRM4 (0.42) | GRM4FDPSTDP1LAP3GRIN2D | |
| Methacrylic Acid SCHEMBL11265929 | 0.76 | TDP1 (0.39) | GRM4TDP1TET2MEN1LMNA | |
| Methacrylic Acid SCHEMBL4928189 | 0.76 | TDP1 (0.39) | GRM4TDP1TET2MEN1KMT2A | |
| SCHEMBL28609591 | 0.75 | GRM4 (0.35) | GRM4PGK1PGK2 | |
| Methacrylic Acid SCHEMBL14631234 | 0.75 | TDP1 (0.47) | FDPSTDP1TET2LMNATSHR | |
| Medronic Acid SCHEMBL9658866 | 0.73 | KDM4E (0.53) | TDP1LAP3GRIN2DGRIN3BGRIN1 | |
| Methacrylic Acid SCHEMBL5477359 | 0.73 | LAP3 (0.39) | FDPSTDP1LAP3GRIN2DGRIN3B | |
| Methacrylic Acid SCHEMBL16668705 | 0.72 | PEPD (0.43) | TDP1PEPDMEN1LMNAHPGD | |
| Methacrylic Acid SCHEMBL7649955 | 0.72 | PEPD (0.43) | TDP1PEPDMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| EP-2277496-A1 | Dental material containing surface-modified fillers | Ivoclar Vivadent AG (LI) | 2011-01-26 | — | — | EP | disclosed |
| EP-1716836-B1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2011-01-19 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
| EP-1148071-B1 | Hydrolysis-stable and polymerisable acrylphosphonic acid mono esters | IVOCLAR VIVADENT AG (LI) | 2004-06-16 | — | — | EP | disclosed |
| US-6710149-B2 | USE OF ACRYLOPHOSPHONIC ACID AS A COMPONENT OF AN ADHESIVE, OF A POLYMER, OF A COMPOSITE, OF A CEMENT, OF A MOLDED ARTICLE AND IN PARTICULAR OF A DENTAL MATERIAL | IVOCLAR VIVADENT AG (LI) | 2004-03-23 | — | — | US | disclosed |
| EP-1148060-B1 | Hydrolysis-stable and polymerisable acrylphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2003-09-10 | — | — | EP | disclosed |
| EP-0909761-B1 | Hydrolysis-stable and polymerizable acryl phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2003-04-02 | — | — | EP | disclosed |
| US-6350839-B2 | THE MONOESTER OF THE PHOSPHONIC ACID GROUP ALSO HAS IMPROVED SOLUBILITY IN POLAR ORGANIC SOLVENTS, AND WATER THAN THE CORRESPONDING ACID; USE IN DENTISTRY | IVOCLAR VIVADENT AG (LI) | 2002-02-26 | — | — | US | disclosed |
| US-20020016384-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid | IVOCLAR VIVADENT AG. | 2002-02-07 | — | — | US | disclosed |
| US-20010044513-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid monoesters | IVOCLAR VIVADENT AG | 2001-11-22 | — | — | US | disclosed |
| EP-1148071-A2 | Hydrolysis-stable and polymerisable acrylphosphonic acid mono esters | Ivoclar Vivadent AG (LI) | 2001-10-24 | — | — | EP | disclosed |
| EP-1148060-A1 | Hydrolysis-stable and polymerisable acrylphosphonic acids | Ivoclar Vivadent AG (LI) | 2001-10-24 | — | — | EP | disclosed |
| US-6172131-B1 | MADE BY REACTING AN ALPHA-HALOMETHACRYLIC ACID ESTER WITH PROTECTED MONO- OR DIFUNCTIONAL PHOSPHONIC ACID ESTERS; USE AS COMPONENT OF DENTAL ADHESIVES DUE TO THEIR ADHESION-PROMOTING PROPERTIES | IVOCLAR AG | 2001-01-09 | — | — | US | disclosed |
| EP-0909761-A1 | Hydrolysis-stable and polymerizable acryl phosphonic acids | IVOCLAR AG (LI) | 1999-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | GRM4 128/4885FDPS 4012/4885TDP1 4617/4885 |
| US-20020016384-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid | PHOSPHO1, PPA1, ABHD16A | GRM4 1827/4885FDPS 666/4885TDP1 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.