Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 9/20 | 0.39 |
| ▸ | AR | P10275 | 6/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648235 | 0.89 | AR (0.41) | PRKAA2GCGRAR | |
| SCHEMBL27525530 | 0.77 | AR (0.42) | AR | |
| SCHEMBL2647867 | 0.77 | AR (0.41) | ARTRPC3TRPC7 | |
| SCHEMBL2662929 | 0.75 | PRKAA2 (0.44) | PRKAA2GCGR | |
| SCHEMBL2647574 | 0.74 | PRKAA2 (0.47) | PRKAA2GCGRDHODH | |
| SCHEMBL2662912 | 0.73 | PRKAA2 (0.45) | PRKAA2GCGR | |
| SCHEMBL2646810 | 0.71 | PRKAA2 (0.47) | PRKAA2GCGR | |
| SCHEMBL27525559 | 0.71 | PRKAA2 (0.51) | PRKAA2GCGRDHODH | |
| SCHEMBL8949900 | 0.65 | GCGR (0.62) | PRKAA2GCGR | |
| SCHEMBL6958229 | 0.65 | GCGR (0.70) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998004528-A2 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | BAYER CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |