Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 12/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963407 | 0.80 | GCGR (0.54) | PRKAA2GCGR | |
| SCHEMBL27525559 | 0.77 | PRKAA2 (0.51) | PRKAA2GCGR | |
| SCHEMBL2662929 | 0.77 | PRKAA2 (0.44) | PRKAA2GCGRCETP | |
| SCHEMBL2647574 | 0.76 | PRKAA2 (0.47) | PRKAA2GCGRCETP | |
| SCHEMBL2646810 | 0.74 | PRKAA2 (0.47) | PRKAA2GCGR | |
| SCHEMBL9072602 | 0.73 | PRKAA2 (0.42) | PRKAA2GCGR | |
| SCHEMBL2648235 | 0.73 | AR (0.41) | PRKAA2GCGRCETP | |
| SCHEMBL2648300 | 0.72 | GCGR (0.70) | GCGR | |
| SCHEMBL6953314 | 0.72 | GCGR (0.54) | PRKAA2GCGR | |
| SCHEMBL6477347 | 0.72 | CETP (0.49) | PRKAA2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |