Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515764 | 0.79 | GCK (0.54) | GCK | |
| SCHEMBL9072903 | 0.73 | NPC1 (0.43) | GCK | |
| SCHEMBL2518491 | 0.71 | GCK (0.51) | GCK | |
| SCHEMBL2657550 | 0.71 | GCK (0.55) | GCK | |
| SCHEMBL2669031 | 0.70 | GCK (0.42) | GCK | |
| SCHEMBL2517228 | 0.69 | GCK (0.56) | GCK | |
| SCHEMBL2669273 | 0.68 | AAK1 (0.47) | GCK | |
| SCHEMBL2649995 | 0.68 | GCK (0.46) | GCK | |
| SCHEMBL6163804 | 0.68 | GCK (0.46) | GCK | |
| SCHEMBL12227754 | 0.67 | GCK (0.40) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |