⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943529 | 0.88 | APP (0.41) | — | |
| SCHEMBL14515804 | 0.78 | PTGS1 (0.33) | — | |
| SCHEMBL1161867 | 0.78 | PTGS1 (0.33) | — | |
| SCHEMBL6208724 | 0.77 | PTGS1 (0.32) | — | |
| SCHEMBL28137832 | 0.77 | PTGS1 (0.32) | — | |
| SCHEMBL6111881 | 0.74 | — | — | |
| SCHEMBL9364342 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL17758466 | 0.73 | EPHX1 (0.52) | — | |
| SCHEMBL2516126 | 0.72 | LMNA (0.41) | — | |
| SCHEMBL167373 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024128473-A1 | COMPOSITION FOR PREVENTING OR TREATING SIDE EFFECTS OF CHOLINESTERASE INHIBITORS | 닥터노아바이오텍 주식회사 | 2024-06-20 | — | — | WO | claimed |
| WO-2023149682-A1 | COMPOSITION COMPRISING BETA BLOCKER AND CHOLINESTERASE INHIBITOR FOR TREATMENT OF NEURODEGENERATIVE DISEASE | 닥터노아바이오텍 주식회사 | 2023-08-10 | — | — | WO | claimed |
| WO-2022163971-A1 | COMPOSITE PHARMACEUTICAL COMPOSITION FOR TREATMENT OF BRAIN DISEASE, COMPRISING CHOLINESTERASE INHIBITOR AND ANTIOXIDANT | 닥터노아바이오텍 | 2022-08-04 | — | — | WO | claimed |
| WO-2024128473-A1 | COMPOSITION FOR PREVENTING OR TREATING SIDE EFFECTS OF CHOLINESTERASE INHIBITORS | 닥터노아바이오텍 주식회사 | 2024-06-20 | — | — | WO | disclosed |
| WO-2023149682-A1 | COMPOSITION COMPRISING BETA BLOCKER AND CHOLINESTERASE INHIBITOR FOR TREATMENT OF NEURODEGENERATIVE DISEASE | 닥터노아바이오텍 주식회사 | 2023-08-10 | — | — | WO | disclosed |
| WO-2022163971-A1 | COMPOSITE PHARMACEUTICAL COMPOSITION FOR TREATMENT OF BRAIN DISEASE, COMPRISING CHOLINESTERASE INHIBITOR AND ANTIOXIDANT | 닥터노아바이오텍 | 2022-08-04 | — | — | WO | disclosed |
| WO-2008098244-A1 | NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR | METABASIS THERAPEUTICS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |