Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15702330 | 0.79 | TSHR (0.50) | TSHRCYP3A4CYP2D6NFKB1THPO | |
| SCHEMBL6904890 | 0.79 | TSHR (0.50) | TSHRCYP3A4CYP2D6NFKB1THPO | |
| SCHEMBL13819753 | 0.69 | — | — | |
| SCHEMBL12773076 | 0.65 | — | — | |
| SCHEMBL5353428 | 0.64 | — | — | |
| SCHEMBL2914504 | 0.64 | — | — | |
| SCHEMBL8506673 | 0.64 | — | — | |
| SCHEMBL19163687 | 0.63 | — | — | |
| SCHEMBL19197762 | 0.63 | — | — | |
| SCHEMBL12773085 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587303-A | HYDROLYSIS OF NITRILE CONTAINING AMINE COMPOUND | NIPPON MINING COMPANY, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0332379-B1 | Production process of L-alpha-amino acids | JAPAN ENERGY CORP (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0332379-A2 | Production process of L-alpha-amino acids | JAPAN ENERGY CORPORATION (JP) | 1989-09-13 | — | — | EP | disclosed |