SCHEMBL6904890

SCHEMBL6904890

CC(N)CSSCC(C)N

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
NFKB1 P19838 1/20 0.50
THPO P40225 1/20 0.50
GMNN O75496 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
PMP22 Q01453 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.44
MAOA P21397 4/20 0.40
MAOB P27338 2/20 0.40
MAPK1 P28482 1/20 0.39
OPRM1 P35372 1/20 0.32
ANPEP P15144 1/20 0.32
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15702330 1.00 TSHR (0.50) TSHRCYP3A4CYP2D6NFKB1THPO
SCHEMBL13819753 0.87
SCHEMBL12773076 0.83
SCHEMBL12773085 0.81
SCHEMBL9073207 0.79 TSHR (0.36) TSHRCYP3A4CYP2D6NFKB1THPO
SCHEMBL3863769 0.77
SCHEMBL550594 0.77
SCHEMBL550638 0.77
SCHEMBL24374520 0.77 SLC7A5 (0.48) ALDH1A1
SCHEMBL24359839 0.77 SLC7A5 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718698-B2 Polyolefin grafted polydiene polymers, and methods of making and using same BRIDGESTONE CORPORATION (JP) 2023-08-08 US disclosed
US-20210230420-A1 Polyolefin Grafted Polydiene Polymers, And Methods Of Making And Using Same BRIDGESTONE CORPORATION (JP) 2021-07-29 US disclosed
EP-3397666-B1 POLYOLEFIN GRAFTED POLYDIENE POLYMERS, AND METHODS OF MAKING AND USING SAME BRIDGESTONE CORP (JP) 2020-08-26 EP disclosed
CN-108473635-B Polyolefin grafted polydiene polymers and methods of making and using the same 株式会社普利司通 2020-08-25 CN disclosed
EP-3079015-B1 PHOTOMASK BLANK, RESIST PATTERN FORMING PROCESS, AND METHOD FOR MAKING PHOTOMASK SHINETSU CHEMICAL CO (JP) 2020-04-29 EP disclosed
US-20180362695-A1 Polyolefin Grafted Polydiene Polymers, And Methods Of Making And Using Same BRIDGESTONE CORPORATION (JP) 2018-12-20 US disclosed
US-8647670-B2 Biocompatible rapid-gelating hydrogel and associated preparation method of spray BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2014-02-11 US disclosed
US-20100144902-A1 BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2010-06-10 US disclosed
EP-0966493-A4 REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS COMMW SCIENT IND RES ORG (AU) 2004-04-21 EP disclosed
US-6344523-B1 POLYIMIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION OF CAMPBELL (AU) 2002-02-05 US disclosed
EP-0966493-A1 REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-12-29 EP disclosed
WO-1998040422-A1 REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144902-A1 BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY CSTB, CAPG, F12 TSHR 1923/4885CYP3A4 1519/4885CYP2D6 2907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.