SCHEMBL907397

SCHEMBL907397

CSCCC(N)C(=O)NC(CC(C)C)C(=O)N(C=O)C(Cc1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.47
FNTB P49356 4/20 0.47
PGGT1B P53609 2/20 0.47
LTA4H P09960 1/20 0.44
MME P08473 1/20 0.43
TACR3 P29371 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4959069 0.87 FNTA (0.43) FNTAFNTBPGGT1BLTA4H
SCHEMBL2213322 0.85 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL2213310 0.85 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL3382819 0.84 ALPI (0.42) FNTAFNTBPGGT1B
Formic Acid SCHEMBL27865482 0.82 FNTA (0.52) FNTAFNTBPGGT1BLTA4HMME
SCHEMBL907360 0.81 FNTA (0.56) FNTAFNTBPGGT1BLTA4HMME
SCHEMBL907359 0.81 FNTA (0.56) FNTAFNTBPGGT1BLTA4HMME
SCHEMBL16430977 0.81 LTA4H (0.58) FNTAFNTBPGGT1BLTA4HMME
SCHEMBL16430978 0.81 LTA4H (0.58) FNTAFNTBPGGT1BLTA4HMME
SCHEMBL3646826 0.81 FNTA (0.56) FNTAFNTBPGGT1BLTA4HMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140166-A2 NOVEL ADJUVANT FOR SUBUNIT OR COMPONENT VACCINES VIROGENETICS CORPORATION (US) 2001-10-10 EP claimed
WO-2000035482-A2 NOVEL ADJUVANT FOR SUBUNIT OR COMPONENT VACCINES VIROGENETICS CORPORATION (US) 2000-06-22 WO claimed
US-5750354-A Lipoxin transport system and uses therefor BRIGHAM AND WOMEN'S HOSPITAL (US) 1998-05-12 US claimed
EP-3669894-A2 NOVEL MULTIFUNCTIONAL COMPOUNDS FOR PHARMACEUTICAL PURPOSES Syntab Therapeutics GmbH (DE) 2020-06-24 EP disclosed
US-10202421-B2 Tumor-targeting compounds SYNTAB THERAPEUTICS GMBH (DE) 2019-02-12 US disclosed
US-20170096452-A1 Novel Tumor-Targeting Compounds SYNTAB THERAPEUTICS GMBH (DE) 2017-04-06 US disclosed
US-20160367620-A1 GLUTATHIONE DEMOPOULOS HARRY B (US) 2016-12-22 US disclosed
US-8470963-B2 Multifunctional compounds for pharmaceutical purposes SKU ASSET MANAGEMENT GMBH (DE) 2013-06-25 US disclosed
US-8209131-B2 Inflammation, allergic diseases, metastatic cancers, pathogen infections; glycosaminoglycan related molecules CURTIN UNIVERSITY OF TECHNOLOGY (AU) 2012-06-26 US disclosed
US-20120010153-A1 NOVEL TUMOR-TARGETING COMPOUNDS SKU ASSET MANAGEMENT GMBH (DE) 2012-01-12 US disclosed
EP-2387421-A1 COMPOUNDS COMPRISING N-FORMYL-METHIONINE RESIDUES AND TUMOR-TARGETING PEPTIDES SKU Asset Management GmbH (DE) 2011-11-23 EP disclosed
EP-1743649-A1 Treatment and diagnosis of infertility using TGF beta or activin The University of Adelaide (AU) 2007-01-17 EP disclosed
US-20070010451-A1 Method of protecting cells against damage and pharmaceutical composition comprising leumorphin POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2007-01-11 US disclosed
EP-0755406-B1 METHOD AND PRODUCT FOR REGULATING CELL RESPONSIVENESS TO EXTERNAL SIGNALS NAT JEWISH CT IMMUN & RESPIRAT (US) 2006-03-08 EP disclosed
US-6872536-B1 Chemotactic peptide antagonists for imaging sites of inflammation BRACCO IMAGING S.P.A. (IT) 2005-03-29 US disclosed
US-20020094549-A1 Screening methods for presqualene diphosphate analogs SERHAN CHARLES N (US) 2002-07-18 US disclosed
US-6395874-B1 A PROTEIN; THERAPY FOR STROKES, ARTHRITIS, PULMONARY ADULT RESPIRATORY DISTRESS SYNDROME, ATHEROSCLEROSIS AND INFLAMMATION OF THE EYE DOHENY EYE INSTITUTE 2002-05-28 US disclosed
EP-1140166-A2 NOVEL ADJUVANT FOR SUBUNIT OR COMPONENT VACCINES VIROGENETICS CORPORATION (US) 2001-10-10 EP disclosed
WO-2000035482-A2 NOVEL ADJUVANT FOR SUBUNIT OR COMPONENT VACCINES VIROGENETICS CORPORATION (US) 2000-06-22 WO disclosed
US-4803197-A ANTIINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1989-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10202421-B2 Tumor-targeting compounds TP53, MYC, KRAS FNTA 190/4885FNTB 138/4885PGGT1B 478/4885
US-20120010153-A1 NOVEL TUMOR-TARGETING COMPOUNDS TP53, TPX2, KRAS FNTA 480/4885FNTB 246/4885PGGT1B 498/4885
US-20170096452-A1 Novel Tumor-Targeting Compounds TP53, TPX2, KRAS FNTA 480/4885FNTB 246/4885PGGT1B 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.