Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 7/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074251 | 1.00 | ALOX5 (0.44) | ALOX5HTTBRAFMAPK3MAPK1 | |
| SCHEMBL9074257 | 1.00 | ALOX5 (0.44) | ALOX5HTTBRAFMAPK3MAPK1 | |
| SCHEMBL9048545 | 0.87 | ALOX5 (0.36) | ALOX5HTTBRAF | |
| SCHEMBL9075885 | 0.87 | ALOX5 (0.36) | ALOX5HTTBRAF | |
| SCHEMBL9075879 | 0.87 | ALOX5 (0.36) | ALOX5HTTBRAF | |
| SCHEMBL9074364 | 0.87 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL9074354 | 0.87 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL9076131 | 0.85 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9076557 | 0.85 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9076555 | 0.84 | ALOX5 (0.42) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |