Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | IL6 | P05231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075258 | 0.94 | S1PR1 (0.42) | S1PR1S1PR3OPRK1OPRM1OPRD1 | |
| SCHEMBL9073818 | 0.94 | S1PR1 (0.35) | S1PR1S1PR3OPRK1OPRM1OPRD1 | |
| SCHEMBL9075398 | 0.93 | SPHK1 (0.42) | S1PR1S1PR3SPHK1 | |
| SCHEMBL9277336 | 0.92 | SPHK1 (0.44) | S1PR1S1PR3SPHK1 | |
| SCHEMBL9074567 | 0.92 | SPHK1 (0.44) | S1PR1S1PR3SPHK1 | |
| SCHEMBL9074412 | 0.92 | SPHK1 (0.44) | S1PR1S1PR3SPHK1 | |
| SCHEMBL9074209 | 0.92 | OPRK1 (0.35) | S1PR1S1PR3OPRK1OPRM1OPRD1 | |
| SCHEMBL9075278 | 0.89 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ALDH1A1RAB9A | |
| SCHEMBL9076142 | 0.88 | S1PR1 (0.42) | S1PR1S1PR3OPRK1OPRM1OPRD1 | |
| SCHEMBL9075385 | 0.87 | SPHK1 (0.42) | S1PR1S1PR3SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545444-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1996-08-13 | — | — | US | disclosed |
| US-5430195-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5414126-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1995-05-09 | — | — | US | disclosed |