Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074766 | 1.00 | ALOX5 (0.35) | ALOX5METPDE3BPDE3ALMNA | |
| SCHEMBL9074771 | 1.00 | ALOX5 (0.35) | ALOX5METPDE3BPDE3ALMNA | |
| SCHEMBL9050252 | 0.87 | ALOX5 (0.41) | ALOX5LMNAMAPTITK | |
| SCHEMBL9051562 | 0.87 | ALOX5 (0.38) | ALOX5METPDE3BPDE3AITK | |
| SCHEMBL9074084 | 0.81 | ALOX5 (0.44) | ALOX5METPDE3BPDE3ALMNA | |
| SCHEMBL9074083 | 0.81 | ALOX5 (0.44) | ALOX5METPDE3BPDE3ALMNA | |
| SCHEMBL9074081 | 0.81 | ALOX5 (0.44) | ALOX5METPDE3BPDE3ALMNA | |
| SCHEMBL9050041 | 0.81 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL9075763 | 0.80 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL9076775 | 0.80 | ALOX5 (0.32) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |