Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 5/20 | 0.34 |
| ▸ | MMP2 | P08253 | 5/20 | 0.34 |
| ▸ | MMP9 | P14780 | 5/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074892 | 1.00 | KDM4E (0.38) | KDM4EMEN1NPC1NFKB1RAB9A | |
| SCHEMBL9074898 | 1.00 | KDM4E (0.38) | KDM4EMEN1NPC1NFKB1RAB9A | |
| Hydrochloric Acid SCHEMBL9074947 | 0.99 | MEN1 (0.37) | KDM4EMEN1NPC1NFKB1RAB9A | |
| Hydrochloric Acid SCHEMBL9074941 | 0.99 | MEN1 (0.37) | KDM4EMEN1NPC1NFKB1RAB9A | |
| Hydrochloric Acid SCHEMBL9224284 | 0.99 | MEN1 (0.37) | KDM4EMEN1NPC1NFKB1RAB9A | |
| Hydrochloric Acid SCHEMBL9075326 | 0.90 | ALOX5 (0.39) | KDM4EMEN1NPC1NFKB1RAB9A | |
| Hydrochloric Acid SCHEMBL9075330 | 0.90 | ALOX5 (0.39) | KDM4EMEN1NPC1NFKB1RAB9A | |
| Hydrochloric Acid SCHEMBL9285079 | 0.89 | ALOX5 (0.36) | MEN1KMT2AALOX5MAPT | |
| SCHEMBL10438711 | 0.88 | SAE1 (0.42) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10438712 | 0.88 | SAE1 (0.42) | KDM4EMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508450-A | INHIBITORY EFFECT ON MAILLARD REACTION AND ANTIOXIDIZING EFFECT; TREATS OR PREVENTS DIABETIC COMPLICATIONS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | claimed |
| EP-0387771-A2 | Benzopyran derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-09-19 | — | — | EP | claimed |