SCHEMBL9075016

SCHEMBL9075016

C=CCc1c(OCCCOc2cc(OCc3ccccc3)c(-c3ccc(F)cc3)cc2CC)cccc1C(=O)c1ccccc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.64
LTB4R2 Q9NPC1 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898601 0.93 LTB4R (0.55) LTB4RLTB4R2
SCHEMBL16256865 0.86 LTB4R (0.51) LTB4RLTB4R2
SCHEMBL16256866 0.85 LTB4R (0.49) LTB4RLTB4R2
SCHEMBL9075582 0.84 LTB4R (0.58) LTB4RLTB4R2
SCHEMBL15110733 0.84 LTB4R (0.71) LTB4RLTB4R2
SCHEMBL9075382 0.83 LTB4R (0.79) LTB4RLTB4R2
SCHEMBL9075483 0.83 LTB4R (0.82) LTB4RLTB4R2
SCHEMBL9074390 0.82 LTB4R (0.79) LTB4RLTB4R2
SCHEMBL9075937 0.81 LTB4R (0.79) LTB4RLTB4R2
SCHEMBL9075581 0.81 LTB4R (0.80) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996036347-A1 USE OF LEUKOTRIENE ANTAGONISTS FOR ALZHEIMER'S DISEASE ELI LILLY AND COMPANY (US) 1996-11-21 WO disclosed