SCHEMBL9075035

SCHEMBL9075035

CC(C)ON=Cc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 17/20 0.44
BCAT2 O15382 15/20 0.44
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8105836 0.89 BCAT1 (0.49) BCAT1BCAT2SMN1; SMN2ALDH1A1CYP2C9
SCHEMBL8105838 0.89 BCAT1 (0.49) BCAT1BCAT2SMN1; SMN2ALDH1A1CYP2C9
SCHEMBL8112922 0.86 BCAT1 (0.44) BCAT1BCAT2SMN1; SMN2ALDH1A1
SCHEMBL7930259 0.86 BCAT1 (0.44) BCAT1BCAT2SMN1; SMN2ALDH1A1
SCHEMBL9230127 0.80
SCHEMBL23635730 0.80 BCAT1 (0.40) BCAT1BCAT2SMN1; SMN2ALDH1A1
SCHEMBL10419155 0.79 BCAT1 (0.42) BCAT1BCAT2SMN1; SMN2ALDH1A1
SCHEMBL10419154 0.79 BCAT1 (0.42) BCAT1BCAT2SMN1; SMN2ALDH1A1
SCHEMBL10530894 0.78 BCAT1 (0.52) BCAT1BCAT2SMN1; SMN2
SCHEMBL9581685 0.75 BCAT1 (0.46) BCAT1BCAT2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486521-A INSECTICIDES UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-01-23 US disclosed
WO-1995025725-A1 PYRIMIDINYL ARYL KETONE OXIMES UNIROYAL CHEMICAL COMPANY, INC. (US) 1995-09-28 WO disclosed