SCHEMBL9075314

SCHEMBL9075314

Cc1cc(C2(c3cc(C)c(O)c(C)c3)CCCC(C(C)C)C2)cc(C)c1O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074141 0.84 ACHE (0.36) ACHEALOX12
SCHEMBL9075884 0.84 ACHE (0.36) ACHE
SCHEMBL2996266 0.81 ACHE (0.58) ACHEESR1ESR2CA1CA2
SCHEMBL9066672 0.80 ACHE (0.61) ACHEESR1ESR2LMNAALOX12
SCHEMBL9074035 0.78 ESR2 (0.52) ESR1ESR2LMNAALOX12
SCHEMBL16581486 0.77 ACHE (0.57) ACHEESR1ESR2CA1CA2
SCHEMBL9067033 0.76 ACHE (0.56) ACHEESR1ESR2CA1CA2
SCHEMBL674882 0.74 ACHE (0.96) ACHEESR1ESR2LMNAALOX12
SCHEMBL673355 0.73 ACHE (1.00) ACHEESR1ESR2LMNAALOX12
SCHEMBL672596 0.73 ACHE (1.00) ACHEESR1ESR2LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
EP-0469403-A2 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
US-5034457-A Polycarbonate for use in molding materials for laminated films and for electronics BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed
US-5010162-A Polycarbonate of alkyl cyclohexylidene bisphenol BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
EP-0387593-A2 Thermoplastic alloys of polycarbonates based on substituted cyclohexylidenbisphenols BAYER AG (DE) 1990-09-19 EP disclosed
EP-0374656-A2 Polycarbonates from alkyl cyclohexylidene diphenols BAYER AG (DE) 1990-06-27 EP disclosed