Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.36 |
| ▸ | THRA | P10827 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642948 | 0.75 | THRB (0.38) | THRBTHRAMEN1KMT2AHRH3 | |
| SCHEMBL17224 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL4908032 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL4384105 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL14862 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL14866 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL10703018 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL396001 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL19971167 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 | |
| SCHEMBL16460 | 0.72 | THRB (0.57) | THRBTHRAMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534393-A | SQUARIC ACID DERIVATIVES FOR LEUCO DYES IN IMAGING | POLAROID CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| US-5286612-A | Mixture of superacid precursor and dye | POLAROID CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5278031-A | Neutralization of acid compounds and reverse coloring | POLAROID CORPORATION (US) | 1994-01-11 | — | — | US | disclosed |