Uridine

Uridine

SCHEMBL9075559

Cc1cn(C2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.78
SLC28A2 O43868 1/20 0.78
SLC29A1 Q99808 1/20 0.78
SLC28A3 Q9HAS3 1/20 0.78
PYGM P11217 3/20 0.60
P2RY2 P41231 3/20 0.56
TK2 O00142 4/20 0.55
P2RY6 Q15077 3/20 0.53
P2RY14 Q15391 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL28025505 1.00 SLC28A1 (0.78) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL10812613 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL2583974 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL14388592 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL2786143 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL12103839 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL10340724 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL453142 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL22143517 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM
SCHEMBL10815567 0.91 PYGM (0.70) SLC28A1SLC28A2SLC29A1SLC28A3PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506122-A EXTRACTING PURINE OR PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE FROM CULTURE OF BACILLUS STEAROTHERMOPHILUS AND USED FOR FORMING NUCLEOSIDES BY REACTING PURINE OR PYRIMIDINE BASE, AS SACCHARIDE RESIDUE AND PHOPHORIC ACID YAMASA SHOYU KABUSHIKI KAISHA (JP) 1996-04-09 US disclosed