Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075602 | 1.00 | TUBB1 (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9075608 | 1.00 | TUBB1 (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9373213 | 0.91 | TUBB4A (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7818176 | 0.89 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7814869 | 0.89 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7814865 | 0.89 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7814862 | 0.89 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7818182 | 0.89 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8886344 | 0.87 | TUBB1 (0.42) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8886351 | 0.87 | TUBB1 (0.42) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530141-A | REDUCES THE CHEMOTAXIS AND RESPIRATORY BURST LEADING TO THE FORMATION OF DAMAGING OXYGEN RADICAL DURING INFLAMMATORY AND IMMUNE RESPONSE | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1996-06-25 | — | — | US | disclosed |
| WO-1994006790-A1 | 2,4-DIARYL-1,3-DITHIOLANES; 2,4-DIARYL-1,3-DIOXOLANES; 2,4-DIARYL-1,3-OXATHIOLANES; AND 2,5-DIARYL-1,3-OXATHIOLANES AS PAF RECEPTOR ANTGONISTS AND INHIBITORS OF 5-LIPOXYGENASE | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1994-03-31 | — | — | WO | disclosed |