Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653233 | 0.88 | TAAR1 (0.44) | TAAR1AOC3MAOBHPGDKCNH2 | |
| Hydrochloric Acid SCHEMBL3506475 | 0.86 | TAAR1 (0.42) | TAAR1AOC3MAOBL3MBTL1AOC2 | |
| SCHEMBL22129794 | 0.80 | TAAR1 (0.47) | TAAR1AOC3MAOBDPP4 | |
| SCHEMBL28767831 | 0.74 | KCNH2 (0.44) | TAAR1AOC3HPGDKCNH2TMEM97 | |
| SCHEMBL22129795 | 0.74 | TAAR1 (0.48) | TAAR1AOC3MAOBKCNH2TMEM97 | |
| SCHEMBL4443662 | 0.74 | TAAR1 (0.52) | TAAR1AOC3MAOBKCNH2TMEM97 | |
| SCHEMBL6246687 | 0.74 | TAAR1 (0.52) | TAAR1AOC3MAOBKCNH2TMEM97 | |
| SCHEMBL18822464 | 0.71 | TRPA1 (0.44) | TAAR1HPGDSIGMAR1LOXL2DPP4 | |
| SCHEMBL8738315 | 0.71 | TRPA1 (0.44) | TAAR1HPGDSIGMAR1LOXL2DPP4 | |
| SCHEMBL9073941 | 0.70 | TAAR1 (0.40) | TAAR1AOC3MAOBKCNH2TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532397-A | Substituted silyl alkylene amines | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5529988-A | Substituted silyl alkylene amines | MERRELL PHARMACEUTICALS INC. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5384312-A | Substituted silyl alkylene amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0291787-B1 | Novel substituted silyl alkylene amines | MERRELL DOW PHARMA (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0291787-A1 | Novel substituted silyl alkylene amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-23 | — | — | EP | disclosed |