Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.88 |
| ▸ | PGR | P06401 | 3/20 | 0.88 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.67 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.67 |
| ▸ | SNCA | P37840 | 1/20 | 0.67 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076389 | 1.00 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11107637 | 0.95 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11107640 | 0.95 | NR1I2 (0.85) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11004976 | 0.95 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11004971 | 0.95 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11008367 | 0.94 | NR1I2 (0.82) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11008371 | 0.94 | NR1I2 (0.82) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL4707015 | 0.94 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL192780 | 0.94 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL27487467 | 0.94 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583216-A | Methods for the manufacture of cephems | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-4973684-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4912212-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4668783-A | Thiazolylacetamido cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-26 | — | — | US | disclosed |
| US-4514565-A | Thiazolylacetamido cephalosphorin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| US-4355160-A | Thiazolylacetamido cephalosporin type compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4298606-A | Thiazolylacetamido compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4205180-A | CHEMICAL INTERMEDIATES FOR NOVEL CEPHALOSPORIN COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-05-27 | — | — | US | disclosed |
| US-4203899-A | Thiazolylacetamido compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4098888-A | THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-07-04 | — | — | US | disclosed |