Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302074 | 0.91 | POLB (0.50) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL7435978 | 0.91 | POLB (0.50) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL9209868 | 0.91 | POLB (0.50) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL7302081 | 0.91 | POLB (0.50) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL7311704 | 0.91 | POLB (0.50) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL10339936 | 0.90 | POLB (0.54) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL10967708 | 0.90 | POLB (0.54) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL10964457 | 0.90 | POLB (0.54) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL10339937 | 0.90 | POLB (0.54) | POLBTDP1KDM4EUSP2ESR1 | |
| SCHEMBL10636932 | 0.90 | POLB (0.54) | POLBTDP1KDM4EUSP2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571807-A | CALCIUM ANTAGONISTS, TREATMENT OF ANGINA AND HYPERTENSION | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-11-05 | — | — | US | disclosed |