Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076479 | 1.00 | ALOX5 (0.33) | ALOX5HTTBRAF | |
| SCHEMBL9076534 | 0.82 | ALOX5 (0.37) | ALOX5HTTBRAF | |
| SCHEMBL9076533 | 0.82 | ALOX5 (0.37) | ALOX5HTTBRAF | |
| SCHEMBL9076538 | 0.82 | ALOX5 (0.37) | ALOX5HTTBRAF | |
| SCHEMBL9076849 | 0.80 | HTT (0.33) | ALOX5HTTBRAF | |
| SCHEMBL9077130 | 0.80 | HTT (0.33) | ALOX5HTTBRAF | |
| SCHEMBL9077136 | 0.80 | HTT (0.33) | ALOX5HTTBRAF | |
| SCHEMBL9076846 | 0.80 | HTT (0.33) | ALOX5HTTBRAF | |
| SCHEMBL9077133 | 0.80 | HTT (0.33) | ALOX5HTTBRAF | |
| SCHEMBL9048977 | 0.74 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |