SCHEMBL9076715

SCHEMBL9076715

COC1(c2cc(F)cc(Sc3ccc(C(C)=NO)cc3)c2)CCOC1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9051325 1.00 ALOX5 (0.31) ALOX5POLB
SCHEMBL9076433 0.89 ALOX5 (0.31) ALOX5
SCHEMBL9049631 0.88 HPGD (0.39) ALOX5
SCHEMBL9047632 0.88 GAA (0.32)
SCHEMBL9047318 0.83 GAA (0.33) ALOX5
SCHEMBL9074809 0.83 POLB (0.30) POLB
SCHEMBL9074807 0.83 POLB (0.30) POLB
SCHEMBL9046853 0.83 ALOX5 (0.35) ALOX5
SCHEMBL9076464 0.83 ALOX5 (0.35) ALOX5
SCHEMBL9076462 0.83 ALOX5 (0.35) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482966-A LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS ZENECA LIMITED (GB) 1996-01-09 US disclosed
US-5332757-A Enzyme inhibitors ZENECA LIMITED (GB) 1994-07-26 US disclosed