Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.57 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078544 | 0.92 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL7272788 | 0.86 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL9413163 | 0.84 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL7280534 | 0.81 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL9079411 | 0.80 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL7281912 | 0.80 | PDE4A (0.87) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL29416766 | 0.79 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL7271255 | 0.79 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL2278414 | 0.79 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL7279910 | 0.79 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484924-A | ANTIALLERGEN, ANTIINFLAMMATORY, ANTIASTHMA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0614897-A1 | IMIDAZONAPHTHYRIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |