Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077210 | 1.00 | ALOX5 (0.39) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9077212 | 1.00 | ALOX5 (0.39) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9048370 | 0.89 | ALOX5 (0.42) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9047635 | 0.87 | ALOX5 (0.39) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9076298 | 0.87 | ALOX5 (0.30) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9076299 | 0.87 | ALOX5 (0.30) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9050113 | 0.87 | ALOX5 (0.30) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9074404 | 0.85 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9074400 | 0.85 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9074407 | 0.85 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |