Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048706 | 0.88 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9076160 | 0.87 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9076156 | 0.87 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9076151 | 0.87 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9048186 | 0.83 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL9046672 | 0.82 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9076574 | 0.81 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9049977 | 0.77 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9049483 | 0.76 | ALOX5 (0.51) | ALOX5ALDH1A1 | |
| SCHEMBL9048645 | 0.76 | ALOX5 (0.44) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |