Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 17/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 16/20 | 0.98 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907464 | 1.00 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907478 | 0.99 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL907346 | 0.98 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907349 | 0.96 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL1707568 | 0.88 | SIRT1 (0.82) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907340 | 0.88 | SIRT1 (0.78) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907692 | 0.88 | SIRT1 (0.78) | SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL907138 | 0.87 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL1707948 | 0.87 | SIRT2 (0.82) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907810 | 0.86 | SIRT1 (0.78) | SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021529-A1 | P53 ACTIVATING COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021529-A1 | P53 ACTIVATING COMPOUNDS | TP53, TP53BP1, SIRT1 | SIRT1 3/4885SIRT2 6/4885SIRT3 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.