Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 17/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 17/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076710 | 0.95 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9078349 | 0.94 | AGTR1 (0.48) | AGTR1AGTR2KDM4EMEN1MLNR | |
| SCHEMBL9078091 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9078103 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9078461 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2KDM4EMEN1MLNR | |
| SCHEMBL9076237 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9076344 | 0.85 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9078924 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2KDM4EMEN1MLNR | |
| SCHEMBL9076714 | 0.85 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9078496 | 0.85 | AGTR1 (0.64) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527815-A | TREATMENT OF HYPERTENSION, CONGESTIVE HEART FAILURE, AND HIGH INTRAOCULAR PRESSURE | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |