Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM6A | O15550 | 1/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216834 | 0.90 | ALDH1A1 (0.52) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL9219060 | 0.87 | KDM4E (0.45) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9078082 | 0.83 | KDM4E (0.40) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL9041329 | 0.81 | KDM4E (0.42) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL9078927 | 0.81 | PARP1 (0.47) | ALDH1A1LMNAKDM4EPARP1NR4A1 | |
| SCHEMBL9041814 | 0.80 | NR4A1 (0.51) | ALDH1A1KDM4EPARP1NR4A1NR4A2 | |
| SCHEMBL9077993 | 0.80 | KDM4E (0.49) | ALDH1A1LMNAALOX12KDM4EL3MBTL1 | |
| SCHEMBL9078669 | 0.77 | MAPT (0.40) | ALDH1A1KDM4ETDP1MAPTTSHR | |
| SCHEMBL9078240 | 0.76 | KDM4E (0.50) | ALDH1A1LMNAKDM4EL3MBTL1KDM4A | |
| SCHEMBL9041045 | 0.76 | CLK1 (0.42) | ALDH1A1LMNAKDM4EL3MBTL1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585382-A | ANTICARCINOGENIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5416089-A | Antitumor agent | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |