Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580804 | 0.83 | GAA (0.39) | NNMTGAAKMT2AHSD17B10NAMPT | |
| SCHEMBL1387584 | 0.82 | NAMPT (0.36) | NNMTGAAKMT2AHSD17B10NAMPT | |
| SCHEMBL9098625 | 0.79 | CHRM3 (0.34) | NAMPT | |
| SCHEMBL13350424 | 0.77 | GAA (0.55) | GAAKMT2AHSD17B10NAMPTHPGD | |
| SCHEMBL4582088 | 0.70 | DRD4 (0.38) | GAAKMT2AHSD17B10NAMPTLMNA | |
| SCHEMBL9079648 | 0.70 | HSD17B10 (0.42) | GAAKMT2AHSD17B10NAMPTHPGD | |
| SCHEMBL4580800 | 0.70 | NAMPT (0.40) | GAAKMT2AHSD17B10NAMPTHPGD | |
| SCHEMBL4582006 | 0.69 | GAA (0.46) | GAAKMT2AHSD17B10NAMPTHPGD | |
| SCHEMBL13044612 | 0.69 | ATM (0.48) | GAAKMT2AHSD17B10NAMPTHPGD | |
| SCHEMBL17865782 | 0.68 | NAMPT (0.58) | GAAKMT2AHSD17B10NAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |