Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580800 | 0.85 | NAMPT (0.40) | HSD17B10GAAKMT2ANAMPTPDE10A | |
| SCHEMBL13350424 | 0.84 | GAA (0.55) | HSD17B10GAAKMT2ANAMPTPDE10A | |
| SCHEMBL4582006 | 0.82 | GAA (0.46) | HSD17B10GAAKMT2ANAMPTPDE10A | |
| SCHEMBL13044612 | 0.75 | ATM (0.48) | HSD17B10GAAKMT2ANAMPTPDE10A | |
| SCHEMBL17865782 | 0.74 | NAMPT (0.58) | HSD17B10GAAKMT2ANAMPTHPGD | |
| SCHEMBL9168713 | 0.74 | NAAA (0.57) | KMT2AALDH1A1MEN1 | |
| SCHEMBL4581387 | 0.74 | NAMPT (0.43) | HSD17B10KMT2ANAMPTKDM4EALDH1A1 | |
| SCHEMBL799425 | 0.73 | NAMPT (0.58) | HSD17B10GAAKMT2ANAMPTHPGD | |
| SCHEMBL19349021 | 0.73 | NAMPT (0.58) | HSD17B10GAAKMT2ANAMPTHPGD | |
| SCHEMBL4582716 | 0.71 | MGLL (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |