Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4742878 | 0.93 | POLB (0.49) | POLBLTA4HKMT2ACRBN | |
| SCHEMBL10794749 | 0.83 | LTA4H (0.51) | POLBLTA4HKMT2ACRBN | |
| Bromide SCHEMBL10799026 | 0.82 | LTA4H (0.50) | POLBLTA4HKMT2ACRBN | |
| SCHEMBL4307734 | 0.82 | LTA4H (0.58) | POLBLTA4H | |
| SCHEMBL4307738 | 0.82 | LTA4H (0.58) | POLBLTA4H | |
| Maleic Acid SCHEMBL10797904 | 0.76 | KMT2A (0.47) | POLBLTA4HKMT2AHRH1CRBN | |
| Fumaric Acid SCHEMBL10797913 | 0.76 | KMT2A (0.47) | POLBLTA4HKMT2AHRH1CRBN | |
| Hydrochloric Acid SCHEMBL6791902 | 0.75 | LTA4H (0.44) | POLBLTA4HCRBNALDH1A1 | |
| SCHEMBL5168025 | 0.74 | LTA4H (0.49) | LTA4HHRH1CRBNCYP3A4CYP2D6 | |
| SCHEMBL6857398 | 0.74 | LTA4H (0.49) | LTA4HHRH1CRBNCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578582-A | Methods of treating ischemia with C2, N6 -disubstituted adenosine derivatives | NOVO NORDISK A/S (DK) | 1996-11-26 | — | — | US | disclosed |
| US-5432164-A | Anticonvulsants | NOVO NORDISK A/S (DK) | 1995-07-11 | — | — | US | disclosed |
| EP-0609375-A1 | NOVEL 2,6-DISUBSTITUTED PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-08-10 | — | — | EP | disclosed |
| WO-1993008206-A1 | NOVEL 2,6-DISUBSTITUTED PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-04-29 | — | — | WO | disclosed |