Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.85 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propyl Fumarate SCHEMBL322230 | 0.92 | HCAR2 (1.00) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL529074 | 0.92 | HCAR2 (1.00) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL322229 | 0.92 | HCAR2 (1.00) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL18546478 | 0.90 | HCAR2 (0.88) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL18546477 | 0.90 | HCAR2 (0.88) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL28061111 | 0.90 | HCAR2 (0.96) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL29143645 | 0.90 | HCAR2 (0.96) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Butyl Fumarate SCHEMBL12981047 | 0.89 | HCAR2 (0.86) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL5607514 | 0.88 | HCAR2 (0.92) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL5607524 | 0.88 | HCAR2 (0.92) | HCAR2ATMMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713877-A1 | QINGHAOSU DERIVATIVES AGAINST AIDS | LUO, Xuande (CN) | 1996-05-29 | — | — | EP | disclosed |