Propyl Fumarate

Propyl Fumarate

SCHEMBL529074

CCCOC(=O)/C=C\C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 1.00
ATM Q13315 1/20 0.61
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APP P05067 1/20 0.45
ALOX5 P09917 1/20 0.44
TSHR P16473 3/20 0.42
HPGD P15428 1/20 0.42
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propyl Fumarate SCHEMBL322230 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL322229 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL29143645 0.98 HCAR2 (0.96) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL28061111 0.98 HCAR2 (0.96) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL5607514 0.96 HCAR2 (0.92) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL5607524 0.96 HCAR2 (0.92) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL18546478 0.94 HCAR2 (0.88) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL6898273 0.94 HCAR2 (0.88) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL18546477 0.94 HCAR2 (0.88) HCAR2ATMMAPTRAB9ANPSR1
Propyl Fumarate SCHEMBL9079003 0.92 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161519-A Ionic polymer and preparation method and application thereof 江苏斯尔邦石化有限公司 2024-12-20 CN claimed
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
EP-4031593-B9 POLYMER LATEX FOR THE PREPARATION OF AN ELASTOMERIC FILM HAVING EXCELLENT STRESS RETENTION PROPERTIES AND SOFTNESS SYNTHOMER SDN BHD (MY) 2024-07-17 EP claimed
EP-4031593-B1 POLYMER LATEX FOR THE PREPARATION OF AN ELASTOMERIC FILM HAVING EXCELLENT STRESS RETENTION PROPERTIES AND SOFTNESS SYNTHOMER SDN BHD (MY) 2024-05-01 EP claimed
US-11958926-B2 Modified polyolefin resin NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2024-04-16 US claimed
EP-4010382-B1 POLYMER LATEX COMPOSITION FOR THE PREPARATION OF AN ELASTOMERIC FILM HAVING SELF-HEALING PROPERTIES SYNTHOMER SDN BHD (MY) 2024-03-20 EP claimed
CN-114920867-B Vinylidene fluoride copolymer with controllable particle size distribution and preparation method thereof 万华化学(四川)有限公司 2024-02-02 CN claimed
US-20230287162-A1 THICKENING AGENT FOR A HYDRO-ALCOHOLIC COMPOSITION COATEX (FR) 2023-09-14 US claimed
CN-113462443-B Diesel antiwear agent composition, preparation method thereof and diesel oil composition 中国石油化工股份有限公司 2023-07-14 CN claimed
EP-4188970-A1 THICKENING AGENT FOR A HYDRO-ALCOHOLIC COMPOSITION COATEX (FR) 2023-06-07 EP claimed
EP-0246467-A2 Photosensitive resin composition and use thereof TOKYO OHKA KOGYO CO., LTD. (JP) 1987-11-25 EP claimed
US-4613650-A PRINTING PAPER COATING; CONJUGATED DIOLEFIN, AROMATIC VINYL COMPOUND, VINYL CYANIDE, UNSATURATED ACID AND ESTER NIPPON ZEON CO., LTD. (JP) 1986-09-23 US claimed
EP-0194054-A2 Adhesive compositions based on phenolic resins and products formed from them SCHENECTADY CHEMICALS, INC. (US) 1986-09-10 EP claimed
US-4578425-A ETHYLENE-ACRYLATE INTERPOLYMER, EPOXY RESIN SCHENECTADY CHEMICALS, INC. (US) 1986-03-25 US claimed
US-4578315-A ETHYLENE-ACRYLATE COPOLYMER, EPOXY RESIN, LAMINATION SCHENECTADY CHEMICALS INC. (US) 1986-03-25 US claimed
US-4461809-A GRAFT POLYMER OF ETHYLENE, PROPYLENE, AND ALKYL ESTER OF OLEFINIC DICARBOXYLIC ACID MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-07-24 US claimed
US-4420599-A TWO STEP-COPOLYMERIZATION AROMATIC VINYL COMPOUND AND HALF-ESTER MALEATE, THEN DEALCOHOLATING IDEMITSU KOSAN COMPANY LIMITED (JP) 1983-12-13 US claimed
EP-0022639-B1 ELECTROSTATOGRAPHIC TONER COMPOSITION AND ELECTROSTATOGRAPHIC DEVELOPER COMPOSITION XEROX CORPORATION (US) 1983-05-25 EP claimed
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US claimed
EP-0022639-A1 Electrostatographic toner composition and electrostatographic developer composition XEROX CORPORATION (US) 1981-01-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A HCAR2 341/4885ATM 1551/4885MAPT 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.