Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.62 |
| ▸ | RARG | P13631 | 13/20 | 0.62 |
| ▸ | RARA | P10276 | 13/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079120 | 1.00 | RARB (0.62) | RARBRARGRARAHDAC11HDAC2 | |
| SCHEMBL8765806 | 0.91 | RARG (0.73) | RARBRARGRARAIKBKBLMNA | |
| SCHEMBL8765815 | 0.91 | RARG (0.73) | RARBRARGRARAIKBKBLMNA | |
| SCHEMBL9079300 | 0.86 | RARB (0.82) | RARBRARGRARAHDAC11HDAC2 | |
| SCHEMBL9079305 | 0.86 | RARB (0.82) | RARBRARGRARAHDAC11HDAC2 | |
| SCHEMBL7687188 | 0.82 | RARA (0.47) | RARBRARGRARAHDAC11HDAC2 | |
| SCHEMBL8461452 | 0.80 | RARA (0.45) | RARBRARGRARAHDAC11HDAC2 | |
| SCHEMBL9130746 | 0.80 | RARA (0.45) | RARBRARGRARAHDAC11HDAC2 | |
| SCHEMBL8458638 | 0.80 | RARG (0.55) | RARBRARGRARAIKBKBLMNA | |
| SCHEMBL7077371 | 0.79 | RARB (0.61) | RARBRARGRARAHDAC11HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547983-A | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1996-08-20 | — | — | US | disclosed |