Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12935809 | 0.81 | MAOB (0.48) | MRGPRX4MAOB | |
| SCHEMBL9326493 | 0.76 | ALOX5 (0.52) | ALOX5MRGPRX4RAB9AADAM17MAOB | |
| SCHEMBL9182358 | 0.76 | ALOX5 (0.53) | ALOX5TLR4TLR2RAB9A | |
| SCHEMBL9311274 | 0.75 | ALOX5 (0.53) | ALOX5MRGPRX4ADAM17 | |
| SCHEMBL278302 | 0.75 | ALOX5 (0.63) | ALOX5TLR4TLR2RAB9A | |
| SCHEMBL9583880 | 0.75 | ALOX5 (0.52) | ALOX5MRGPRX4 | |
| SCHEMBL9081529 | 0.74 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9325937 | 0.74 | ALOX5 (0.57) | ALOX5MRGPRX4ADAM17 | |
| SCHEMBL9325922 | 0.74 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9311280 | 0.74 | ALOX5 (0.56) | ALOX5MRGPRX4ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519022-A | α, α dialkylbenzyl derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-05-21 | — | — | US | disclosed |
| US-5288742-A | Lipoxygenase inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-22 | — | — | US | disclosed |
| EP-0505122-A1 | Alpha, alpha-dialkylbenzyl derivatives | ZENECA LIMITED (GB) | 1992-09-23 | — | — | EP | disclosed |