Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498071 | 0.89 | BCHE (0.43) | TBXAS1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1716157 | 0.84 | CYSLTR2 (0.50) | TBXAS1ALDH1A1CYP1A2CYP2C19CYSLTR2 | |
| SCHEMBL5962655 | 0.80 | NAMPT (0.41) | TBXAS1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27788468 | 0.79 | TBXA2R (0.51) | ALDH1A1FFAR1USP5 | |
| SCHEMBL8024424 | 0.79 | TBXAS1 (0.53) | TBXAS1ALDH1A1CYP1A2CYP2C19CYSLTR2 | |
| SCHEMBL1677568 | 0.78 | FFAR1 (0.54) | ALDH1A1FFAR1 | |
| SCHEMBL31462398 | 0.77 | TBXAS1 (0.55) | TBXAS1ALDH1A1CYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL21100871 | 0.76 | MAPT (0.46) | ALDH1A1CYP2C19HDAC3HDAC1HDAC2 | |
| SCHEMBL23689570 | 0.75 | SLC6A2 (0.42) | ALDH1A1CYP2C19 | |
| SCHEMBL3424021 | 0.75 | SLC6A2 (0.42) | ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569665-A | Peptidyl derivatives and their use as metalloproteinases inhibitors | CELLTECH LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |
| EP-0605682-A1 | PEPTIDYL DERIVATIVES AND THEIR USE AS METALLOPROTEINASES INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993024449-A1 | PEPTIDYL DERIVATIVES AND THEIR USE AS METALLOPROTEINASES INHIBITORS | CELLTECH LIMITED (GB) | 1993-12-09 | — | — | WO | disclosed |