Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079464 | 0.80 | TSHR (0.39) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL30923543 | 0.75 | SLC6A4 (0.45) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL18470550 | 0.74 | TAAR1 (0.50) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL14431333 | 0.74 | TAAR1 (0.50) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL416895 | 0.74 | TAAR1 (0.50) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL2408250 | 0.72 | RIPK1 (0.35) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL20306752 | 0.72 | RIPK1 (0.45) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL7623734 | 0.72 | TSHR (0.43) | RIPK1CHRM2ADRA1ASLC6A4TSHR | |
| SCHEMBL9360478 | 0.71 | RIPK1 (0.45) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL9079423 | 0.71 | TSHR (0.31) | RIPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523444-A | REACTING (SUBSTITUTED)AROMATIC COMPOUNDS WITH ALLYLCHLOROSILANES IN PRESENCE OF LEWIS ACID CATALYSTS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-06-04 | — | — | US | disclosed |