Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080176 | 0.89 | MEN1 (0.42) | SCN5ASCN9ANPC1RAB9ATYK2 | |
| SCHEMBL9081129 | 0.85 | SMN1; SMN2 (0.39) | SCN5ASCN9ANPC1RAB9ATYK2 | |
| SCHEMBL9080721 | 0.83 | KMT2A (0.46) | TYK2MEN1KMT2ACRHBPHTT | |
| SCHEMBL9082025 | 0.83 | MEN1 (0.39) | NPC1RAB9ATYK2MEN1KMT2A | |
| SCHEMBL9079922 | 0.82 | EPHB3 (0.39) | SCN5ASCN9ATYK2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9227723 | 0.81 | NPC1 (0.43) | IRAK4SCN5ASCN9ANPC1RAB9A | |
| SCHEMBL9080374 | 0.80 | RECQL (0.48) | NPC1RAB9ATYK2MAPTKMT2A | |
| SCHEMBL9227383 | 0.80 | NR1H2 (0.41) | TYK2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9080651 | 0.79 | KMT2A (0.44) | TYK2MAPTMEN1KMT2ACRHBP | |
| Hydrochloric Acid SCHEMBL9080890 | 0.79 | SCN5A (0.38) | IRAK4SCN5ASCN9ATYK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |