Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 6/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CDK14 | O94921 | 2/20 | 0.36 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080176 | 0.86 | MEN1 (0.42) | EPHB3HPGDMEN1CRHBPHTT | |
| SCHEMBL9081129 | 0.86 | SMN1; SMN2 (0.39) | PTGESNR1H2NR1H3HPGDMEN1 | |
| SCHEMBL9227383 | 0.83 | NR1H2 (0.41) | NR1H2NR1H3HTTSMN1; SMN2TYK2 | |
| SCHEMBL9079754 | 0.82 | IRAK4 (0.47) | MEN1CRHBPHTTKMT2ACRHR2 | |
| SCHEMBL9082025 | 0.80 | MEN1 (0.39) | EPHB3PTGESHPGDMEN1CRHBP | |
| Hydrochloric Acid SCHEMBL9081559 | 0.80 | CDK14 (0.41) | MEN1CRHBPHTTKMT2ACRHR2 | |
| SCHEMBL9081761 | 0.79 | F2R (0.42) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9080721 | 0.79 | KMT2A (0.46) | EPHB3PTGESHPGDMEN1CRHBP | |
| SCHEMBL9079941 | 0.78 | MEN1 (0.42) | PTGESMEN1CRHBPHTTKMT2A | |
| SCHEMBL9080651 | 0.77 | KMT2A (0.44) | EPHB3PTGESHPGDMEN1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |